TRANSLATIONAL PHYSIOLOGY Effects of adlay hull extracts on uterine contraction and Ca mobilization in the rat
نویسندگان
چکیده
Shih-Min Hsia, Yueh-Hsiung Kuo, Wenchang Chiang,* and Paulus S. Wang* Cardinal Tien College of Healthcare and Management; Graduate Institute of Food Science and Technology, Center for Food and Biomolecules, College of Bioresources and Agriculture, National Taiwan University, Taipei; Tsuzuki Institute for Traditional Medicine, College of Pharmacy, China Medical University, Taichung; Department of Physiology, School of Medicine, National Yang-Ming University, Taipei; and Department of Medical Research and Education, Taipei City Hospital, Taipei, Taiwan
منابع مشابه
Effects of adlay hull extracts on uterine contraction and Ca2+ mobilization in the rat.
Dysmenorrhea is directly related to elevated PGF(2alpha) levels. It is treated with nonsteroid antiinflammatory drugs (NSAIDs) in Western medicine. Since NSAIDs produce many side effects, Chinese medicinal therapy is considered as a feasible alternative medicine. Adlay (Coix lachryma-jobi L. var. ma-yuen Stapf.) has been used as a traditional Chinese medicine for treating dysmenorrhea. However,...
متن کاملEffects of ketotifen on oxytocin-induced contraction in the isolated rat uterus
Preterm labor is one of the major causes of neonatal mortality and morbidity. Despite significant improvement in care for premature neonates, the most suitable and inexpensive treatment is prevention of preterm labor by inhibiting uterine contractions. The aim of this research is to obtain scientific evidence for the relaxant effect of ketotifen on the rat uterus and to provide the preclinica...
متن کاملRole of Ca2+ on uterine force stimulated by a glycoside from the root of Dalbergia saxatilis.
Uterine muscle contraction is dependent on external Ca2+ and Ca2+ release from cytoplasmic storage sites. In this study, the mechanism of Ca2+ mobilization in uterine muscle cells by glycoside, dalsaxini, isolated from the root of D. Saxatilis was investigated in the rat. Uterine muscle contractility stimulated by dalsaxin was concentration dependent (ED50 0.13 mg/ml) and was significantly atte...
متن کاملInotropic and chronotropic effects of new cilostamide derivatives on isolated rat atria
Introduction: It was shown in a previous study, that MCPIP, a cilostamide derivative, increased atrial contraction force without changing contraction rate. To improve this property, two new derivatives of cilostamide were synthesized and their effects on PDE3 activity and isolated rat atria contraction were investigated. Methods: The inhibitory effect of each compound on PDE3 enzyme was dete...
متن کاملComparing the effects of IV infusion of 10% dextrose and 40 IU/L of oxytocin on uterine contraction after Cesarean section
Background: Uterine bleeding is an important side effect of cesarean section which is due to non contractile uterine. The aim of this study was to compare the effect of 10% dextrose (IV infusion) and 40 IU/L oxytocin (IV infusion) on uterine contraction. Materials and Methods: This research was a double-blinded randomized clinical trial (RCT) study. 120 women were equally included in the tw...
متن کامل